Home / Neurology and Neurosurgery / How to Perform a Lumbar Puncture / Contraindications of a Lumbar Puncture

Contraindications of a Lumbar Puncture

A lumbar puncture (LP) is contraindicated in the following scenarios:

  1. Patients with bleeding diathesis, e.g. severe coagulopathy (INR >1.4) and thrombocytopenia (platelet <50 x 109/L). If coagulopathy or thrombocytopenia is not corrected prior to the procedure, spinal hematomas resulting in spinal cord compromise may result.
  2. Patients with increased intracranial pressure due to an intracranial lesion causing mass effect or significant cerebral oedema. In these circumstances, a LP may cause cerebral herniation.
  3. Patients with an epidural abscess.

Welcome to the HKU eLearning Platform in Clinical Neurosciences!

If this is the first time you have accessed the platform, we would be most grateful if you could let us know a little bit about you.


What is your occupation?




Medical doctor




How did you hear about this platform?