This is a patient with neurofibromatosis type 1, an autosomal dominant neuro-cutaneous disorder. In the first two photos (Figures 1 and 2), multiple neurofibromasas well as café-au-lait spots are present on the trunk and upper limbs. In the third and forth photo (Figures 3 and 4), freckling can be seen at the axillary and inguinal region.

Other features of neurofibromatosis type 1 include optic glioma, Lisch nodules (iris harmatomas), osseous lesions (e.g. sphenoid dysphasia or thinning of long bones), whilst features of neurofibromatosis type 2 include bilateral eighth nerve palsy.

Welcome to the HKU eLearning Platform in Clinical Neurosciences!

If this is the first time you have accessed the platform, we would be most grateful if you could let us know a little bit about you.


What is your occupation?




Medical doctor




How did you hear about this platform?